|
|
Created by Katrina Oschmann
almost 5 years ago
|
|
signal transduction pathway (background info)
quorum sensing
3 ways cells can communicate
direct contact*
local signaling*
long distance signaling
3 stages of cell signaling
reception
transduction
response
G-protein coupled receptors
G-protein coupled receptors steps
receptor tyrosine kinases
receptor tyrosine kinases steps
ion channel receptors (steps)
intracellular receptors (steps/examples)
transduction: cascades of molecular interactions relay signals from receptors to target molecules in the cell
signal transduction pathway (phosphorylation cascade)
protein kinase
protein phosphorylates
Small Molecules and Ions as Second Messengers
cyclic AMP (cAMP)
Calcium ions (Ca2+)
low calcium ion concentration in the cell maintained through -
inositol triphosphate (IP3)
response (cell signaling)
nuclear response
cytoplasmic response
4 ways to fine tune a cellular response
signal amplification
specificity of cell signaling and coordination of the response
signaling efficiency: scaffolding proteins and signaling complexes
termination of the signal
dna transcription
Hide known cards