14101926
| Question | Answer |
| Trade names | Aeron, Apoven, Atrovent, Ipatren uni-dose, Ipravent, Univent |
| Therapeutic class | bronchodilator |
| Pharmacological class | anticholinergic = muscarinic antagonist |
| Indications | Asthma COPD Bronchcospasm during or after surgery Use during intubation |
| Action | Promotes bronchodilation by ipratropium binding competitively to cholinergic receptors in the bronchial smooth muscle thereby blocking the bronchoconstrictor actions of the acetylcholine mediated vagal impulses |
| Metabolism & excretion | Partially metabolised in liver, Primarily eliminated renally via active secretion |
| Half-life | 2-4 hours |
| contraindications/ precautions | Contraindicated in individuals hypersensitive to drug or to atropine or any of its derivatives and in those with a history of hypersensitivity to soya lecithin or related food products such as soybeans and peanuts |
| Possible adverse reactions | CNS: dizziness, headache, pain, nervousness CVS: palpitations, chest pain ENT: rhinitis, pharyngitis, sinusitis EYE: blurred vision GI: nausea, GI distress, dry mouth RESP: upper resp tract infection, bronchitis, cough, dyspnoea, bronchospasm SKIN: rash Other: flu-like symptoms |
| Education | - warn patient that med is not for acute relief - Ask patient to show how they use their inhaler |
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