1479378
| Question | Answer |
| Anaemia | Low blood haemoglobin concentration |
| Microcytic | Small MCV |
| Microcytic | Failure of haemoglobin synthesis (hence smaller erthrocytes) |
| Microcytic | Caused by iron deficiency as a result of gradual blood loss e.g. menstruation, GIT lesions or cancers and parasitic infection |
| Normocytic | Normal MCV |
| Normocytic | Red blood cell production is normal, but is a result of acute blood loss. |
| Macrocytic | Large MCV |
| Macrocytic | Failure in DNA synthesis and cell division (during erythropoeisis). Folic acid (thymine synthesis) and Vit B12 are essential for division. |
| Macrocytic | Vit B12 deficiency: pernicious (gradual but harmful) anaemia Folic acid deficiency: pregnancy |
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