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Description
Flashcards by Jenna Paterson, updated more than 1 year ago
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Created by Jenna Paterson
about 5 years ago
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| Question | Answer |
| What drug class is allopurinol, and what is it used to treat? | Xanthine-oxidase inhibitor - prevents breakdown of purines which produce uric acid. Used to treat gout |
| What are the side effects of allopurinol? | GI upset - diarrhoea |
| What should you beware of when prescribing azathioprine and allopurinol together? | Azathioprine is metabolised into mercaptopurine and therefore its breakdown is slowed down when co-prescribed with allopurinol. It should therefore be replaced with an alternative agent or the dose of azathioprine reduced to take into account the effects of allopurinol on metabolism. |
| When should allopurinol be given? | At least 2 weeks after an acute attack of gout, as it can precipitate acute attacks. |
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