536802
Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
over 11 years ago
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| Question | Answer |
| Alpha-Methyl-P-Tyrosine- Method of Action | Competitive inhibitor of tyrosine hydroxylase |
| Alpha-Methyl-P-Tyrosine- Effect | Inhibits catecholamine synthesis |
| Alpha-Methyl-P-Tyrosine- Treats | Hypertension |
| Alpha-Methyl-DOPA- Mode of Action | Outcompetes DOPA for DOPA decarboxylase |
| Alpha-Methyl-DOPA- Effect | Inhibits catecholamine synthesis, but converted by pathway in to less active form of noradrenaline |
| Alpha-Methyl-DOPA- Treats | Hypertension |
| Reserprine- Mode of Action | Blocks storage vesicles, preventing dopamine storage |
| Reserprine- Effect | NA accumulates in the cytoplasm and is destroyed by Monoamine Oxidase |
| Reserprine- Treats | Psychosis and hypertension |
| Reserprine- Major Side Effect | Depression |
| Guanathidine- Mode of Action | Displaces noradrenaline from the vesicle |
| Guanathidine- Effect | NA is broken down by Monoamine Oxidase |
| Guanethidine- Treats | Blood pressure (red. cardiac output & causes vasodilation) |
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