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Created by gina_evans0312
over 11 years ago
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| Question | Answer |
| Inslun:Glucaon Ratio | 0:0.15 |
| Blood Glucose Levels | Will vary in this state, and change the metabolic processes with them |
| Liver- Glucose Uptake | Since plasma glucose as fallen, the GLUT2 receptors can no longer take up glucose |
| Liver- Glycogen | Broken down by glycogen phosphatase to glucuse |
| Liver- Glucose | Either uses GLUT2 to exit the liver or is made into Phospoenoylpyruvate (PEP) |
| Liver- Alanine/Lactate | Enters liver to make Phosphoenoylpyruvate (PEP) |
| Liver- Phosphoenoylpyruvate (PEP) | Blood Glucose Low- Made into glucose Blood Glucose High- Made into pyruvate |
| Liver- Amino Acids | Made from pyruvate in other cells, then used to make pyruvate in the liver |
| Liver- Pyruvate | Blood Glucose High- Makes acetyl CoA Blood Glucose low- made back into PEP |
| Liver- Acetyl CoA | Depending on blood glucose levels, either TCA or TAG generation |
| Adipose Tissue- Glucose Transporters | Still GLUT4, but fall in numbers due to decrease in insulin |
| Adipose Tissue- Glycolysis/TAG Synthesis | Switched off entirely (not enough glucose entering for enzymes to be in active states) |
| Adipose Tissue- TAGs | Broken down in to glycerol (for transport to liver) or to be used as fuel by muscle |
| Muscle- Glucose Transporters | Reduced Nos of GLUT4 |
| Muscle- Glucose | Little is converted into glycogen, most is used |
| Muscle- Glucagon Receptors | None- so glycogen only breaks down according to the muscles needs |
| Muscle- F.A's | Enter from blood and used to generate pyruvate for fuel |
| Muscle- Protein | Broken down to Alanine and transported to the liver to make glucose |
| Muscle- Pyruvate | Made into glutamine (and transported to liver) or generates lactose during exercise |
| Brain Tissue | Stays the same (brain can't use F.As) |
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