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Created by Victoria Wright
over 8 years ago
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| Question | Answer |
| Starling Curve Force of contraction is proportional to what? | Force of contraction is proportional to enddiastolic length of cardiac muscle fiber (preload). |
| Starling Curve Enddiastolic length of cardiac muscle fiber (preload) is proportional to what? | Force of contraction is proportional to enddiastolic length of cardiac muscle fiber (preload). |
| Starling Curve What do catecholamines do to contractility? | Increase contractility |
| Starling Curve What do positive inotropes (eg digoxin) do to contractility? | Increase contractility |
| Starling Curve What does loss of myocardium (eg MI) do to contractility? | Decrease contractility |
| Starling Curve What do β-blockers (acutely) do to contractility? | Decrease contractility |
| Starling Curve What do non-dihydropyridine Ca2+ channel blockers do to contractility? | Decrease contractility |
| Starling Curve What does dilated cardiomyopathy do to contractility? | Decrease contractility |
| Starling Curve There is increased contractility with what? | With catecholamines, positive inotropes (eg, digoxin). |
| Starling Curve There is decreased contractility with what? | With loss of myocardium (eg, MI), β-blockers (acutely), non-dihydropyridine Ca2+ channel blockers, dilated cardiomyopathy. |
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Exercise |
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Normal |
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HF + digoxin |
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HF |
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Stroke volume (or CO) |
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Ventricular EDV (preload) |
| Resistance, pressure, flow ΔP = ? | ΔP = Q × R |
| Resistance, pressure, flow Q × R = ? | ΔP = Q × R |
| Resistance, pressure, flow Similar to Ohm’s law: ΔV = ? | Similar to Ohm’s law: ΔV = IR |
| Resistance, pressure, flow Volumetric flow rate (Q) = ? | flow velocity (v) × cross-sectional area (A) |
| Resistance, pressure, flow flow velocity (v) × cross-sectional area (A) = ? | Volumetric flow rate (Q) = flow velocity (v) × cross-sectional area (A) |
| Resistance, pressure, flow driving pressure (ΔP) / flow (Q) = ? | Resistance |
| Resistance, pressure, flow (8η (viscosity) × length) / (πr4) =? | Resistance |
| Total resistance of vessels in series? | Look in book RT = R1 + R2 + R3 . . . |
| Total resistance of vessels in parallel? | Look in book 1/RT = 1/R1 + 1/R2 + 1/R3.... |
| What have the highest total cross-sectional area? | Capillaries have highest total cross-sectional area and lowest flow velocity. |
| What have the lowest flow velocity? | Capillaries have highest total cross-sectional area and lowest flow velocity. |
| What drives flow from high pressure to low pressure? | Pressure gradient drives flow from high pressure to low pressure. |
| Pressure gradient drives flow from what to what? | Pressure gradient drives flow from high pressure to low pressure. |
| What account for most of TPR? | Arterioles account for most of TPR. |
| Arterioles account for most of what? | Arterioles account for most of TPR. |
| What provide most of blood storage capacity? | Veins provide most of blood storage capacity. |
| Veins provide most of what? | Veins provide most of blood storage capacity. |
| Viscosity depends mostly on what? | Viscosity depends mostly on hematocrit. |
| What depends mostly on hematocrit? | Viscosity depends mostly on hematocrit. |
| What happens to viscosity in hyperproteinemic states (eg, multiple myeloma)? | Viscosity increases |
| What happens to viscosity in polycythemia? | Viscosity increases |
| What happens to viscosity in anemia? | Viscosity decreases |
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