Exam 2: Second-Generation Sulfonylureas

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College NUR 325 Mind Map on Exam 2: Second-Generation Sulfonylureas, created by Jasper McClellan on 10/07/2022.
Jasper McClellan
Mind Map by Jasper McClellan, updated more than 1 year ago
Jasper McClellan
Created by Jasper McClellan over 3 years ago
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Exam 2: Second-Generation Sulfonylureas
  1. Nursing interventions
    1. Intermittent glucose monitoring
      1. Obtain baseline BUN, Cr, and LFTs
        1. Continue monitoring BUN and Cr if over 65
        2. Pharmacological Action
          1. Stimulates release of insulin from the pancreas
          2. Extra information
            1. Less effective over time
              1. Taken 30 minutes before breakfast
              2. Pharmokinetics
                1. Excreted through urine
                  1. Metabolized in the liver
                  2. Adverse effects
                    1. Hypoglycemia
                      1. Nausea
                        1. Heartburn
                          1. Photosensitivity
                          2. Contraindications
                            1. Sulfa allergy
                              1. Hepatic/Renal Impairment
                                1. Pregnancy/Lactation
                                  1. Diabetic ketoacidosis
                                  2. Drug interactions
                                    1. Beta-blockers (suppress insulin release)
                                      1. Disulfiram-like reaction
                                        1. Drugs that can interact to cause hypoglycemia
                                          1. sulfonamide antibiotics
                                            1. Acute alcohol ingestion
                                              1. NSAIDs
                                                1. cimetidine (Tagamet)
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