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Enterobacteria

Description

Mind Map on Enterobacteria, created by sam.hilton on 06/05/2013.

Mind Map by sam.hilton, updated more than 1 year ago

	Created by sam.hilton over 12 years ago

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Resource summary

Enterobacteria

Salmonella
1. Cycle of transmission
2. Salmonellosis
  1. Secretion system
    1. Type 1 & 2
  2. Effector proteins
    1. SopE
      1. Membrane ruffling
    2. SipA
      1. Aids process
    3. SipB
      1. Induce inflammation
    4. SopA
      1. Neutrophils-inflammation
    5. Sif
      1. Forms filaments
    6. Ssef
      1. Redirests golgi traffic
Shigella
1. Shigellosis
  1. Virulance factors
    1. IpaC
      1. Cdc42 & Rac1
        Actin polymerisation
    2. IpaD
      1. lossens focal adhesions
    3. VirA
      1. Rho GTPases
        Destabilises microtubules
    4. VirF
      1. Induces gene expression at 37
    5. Shigella protrusions
      1. IcsA
        Binds N-WASP
  2. Secretion system
    1. Type 3
    2. LPS glucosylation
Helicobacter Pylori
1. Symptoms
  1. Gastic ulcers
  2. Duodenal ulcers
  3. Inflammation
    1. MALT lymphoma
    2. gastric carcinoma
2. Virulence factors
  1. Flagella
  2. Urease
    1. Diagnosis
      1. 13C urea test
      2. pH sensitive biopsy
  3. Adhesins
  4. Secretion systems
    1. Type 4
  5. CagA toxins
    1. SHP2 activated
      1. Erk Map Kinase
      2. Hummingbird phenotype
        Increased motility
  6. Vacuolating toxins
    1. Hexameric pore
      1. Apoptosis
    2. P37
    3. P58
  7. LPS immune mimcry

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