Question 1
Question
What is the purpose of Coombs control cells?
Answer
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To ensure that AHG tests with negative results are not the false negatives
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To ensure that washing removed all unbound antibody
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To ensure that AHG was not omitted or inactivated
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All of the above
Question 2
Question
What is a positive DAT?
Answer
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In vitro sensitization of RBC with antigen
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In vitro sensitization of RBC with antibody
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In vivo sensitization of RBC with antibody
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In vivo sensitization of RBC with antigen
Question 3
Question
A positive autocontrol in antibody detection procedures is usually indicative of:
Answer
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Inadequate washing
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Positive DAT
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Positive IAT
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two of the above
Question 4
Question
Why is it important to match the lot number on the panel cells?
Answer
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The ABO group will change from lot to lot
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Pattern of reactions will change from lot to lot
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It is a requirement of the FDA
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All of the above
Question 5
Question
In interpreting an antibody screen, which of the following questions might be asked to decipher the class of antibody?
Question 6
Question
What is an elution?
Answer
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a technique used to dissociate IgM antibodies from sensitized RBCs
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a technique used to dissociate IgG antibodies from sensitized RBCs
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a technique used to reduce the zeta potential enhancing antigen binding
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none of the above
Question 7
Question
What is tested in an antibody screen?
Answer
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Patient red cells are tested against group O reagent screening cells
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Patient serum is tested against group AB reagent screening cells
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Patient serum is tested against group O reagent screening cells
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Patient serum is tested against group A reagent screening cells
Question 8
Question
What might a positive antibody screen and a negative autocontrol indicate?
Answer
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An alloantibody is coating donor cells after a transfusion
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An autoantibody has been detected
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An alloantibody has been detected
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Drug-induced antibody reacting with patient cells.
Question 9
Question
When might you suspect multiple antibodies in a patient's serum?
Answer
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Pattern of reactivity not fitting a single antibody
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Variation in phase of reactivity
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Variation in antibody reactivity strength
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All of the above
Question 10
Question
One drop of Coombs control cells was added to a negative antibody screen. No agglutination was observed after centrifugation. What course of action is taken?
Question 11
Question
What is the shipping temp requirement for plasma?
Answer
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1 to 6 degree F
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1 to 6 degree C
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-18 or higher degree F
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-18 or lower degree C
Question 12
Question
Which of the following may not be used as a patient identifier?
Question 13
Question
Which of the following is not an enhancement media?
Question 14
Question
Additive solutions are approved for storage of red blood cells for how many days?
Question 15
Question
What is the current storage time and storage temp for platelet concentrates and apheresis platelet components?
Answer
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5 days at 1 to 6 degrees C
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5 days at 24 to 27 degrees C
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5 days at 20 to 24 degrees C
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7 days at 22 to 24 degrees C
Question 16
Question
Whole blood and RBC units are stored at what temperature?
Answer
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1 to 6 C
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20 to 24 C
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37 C
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24 to 27 C