Question 1
Question
1.A 29-year-old man is bothered by a "cold sore" on his upper lip. After a week, he notices the appearance of several rounded, slightly erythematous lesions on the palms of his hands averaging 0.4 to 0.8 cm in size. Each of the lesions has a targetoid appearance with a central dark red area. After a course of acyclovir, the lesions on his hands disappear. Which of the following conditions did he most likely have:
Answer
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Erythema multiforme
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Molluscum contagiosum
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Keratoacanthoma
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Impetigo
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Pemphigus vulgaris
Question 2
Question
What do we give to treat generalised putular psoriasis?
Answer
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Methotrexate
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Cyclosporine
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Topical corticosteroids
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Retinoids
Question 3
Question
1. A 17-year-old girl has the onset of "hives" over the past 3 hours. On physical examination there are irregular, slightly raised, erythematous patches from 1 to 6 cm in size over all surfaces of her body. The lesions are pruritic. The lesions gradually fade over the next day without therapy. Which of the following is the most likely diagnosis?
Answer
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Prick test
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Patch test
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Tzanck test
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Skin biopsy
Question 4
Question
4. Three children with ages from 5 to 10 in a family are all affected by itching lesions on their hands for the past 2 weeks. On physical examination there are erythematous areas with superficial excoriation on the fingers and dorsa of the hands. These areas are linear to ovoid. Application of lindane-containing cream results in resolution of the lesions within a week. Infection with which of the following did these children most likely have?
Question 5
Question
5. A 9-year-old girl has developed a skin rash over the past 2 days. On physical examination there are vesicular lesions from 1 to 5 cm in diameter on her extremities and trunk. There are 2 lesions on her buccal mucosa. These lesions have a central red nodule surrounded by a zone of erythema. This child was given antibiotic therapy for a otitis media one week ago. What is the most likely diagnosis?
Question 6
Question
8.Trauma to normal skin in psoriasis patients often results days later in new psoriatic lesions. This is a description of:
Answer
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a. Köbner phenomenon
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b. Gottron's sign
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b. Auspitz sign
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c. Candle sign
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e. Groover sign
Question 7
Question
9. Gottrons sign belongs to which disease;
Answer
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Morphea
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DLE
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SLE
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Dermatomyositis
Question 8
Question
9.Over the past 4 months a 25-year-old woman has noted the appearance of a skin rash on her face when she spends more than an hour in the sun. On physical examination there is an erythematous malar skin rash. Laboratory studies show a positive antinuclear antibody (ANA) test with a titer of 1:256 and anti-double stranded DNA titer of 1:256. A punch biopsy of non- sun exposed skin is performed. Immunofluorescence staining on this normal skin reveals band- like deposition of IgG and C3 at the dermal-epidermal junction. Which of the following immunologic disorders is she most likely to have?
Answer
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Polymyositsidermatomyosits
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b) Discoid lupus erythematosus (DLE)
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c) Systemic sclerosis (SS)
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d) Systemic Lupus Erythematosus (SLE)
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e) Graf versus host disease (GVHD)
Question 9
Question
10.Match the first line treatment for early syphilis:
Question 10
Question
10.Match the first line treatment for early Erisypelas:
Question 11
Question
11. Which of the following test is used in confirming early congenital syphilis:
Answer
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a. VDRL
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b. FTA –ABS IgG
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c. USR
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d. FTA – ABS IgM
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e. TPHA
Question 12
Question
12. Which of the following enzymes are used by HIV DNA —> RNA replication and for integration
Answer
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a. RNA polymerase, reverse transcriptase
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b. RNA polymerase, integrase
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c. Integrase
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d. Reverse transcriptase
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e. Integrase, reverse transcriptase
Question 13
Question
13. Not characteristic of morphea
Answer
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a. Hypopigmentation
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b. Hyperpigmentation
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c. Lung fibrosis
Question 14
Question
14. Which of the following it not used as an exfoliator
Answer
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Urea
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Lactic acid
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Salicylic acid
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Retinoids
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Eucerin
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Click me as correct!!
Question 15
Question
15. Some long as bs about systemic generalised? psoriasis treatment
Question 16
Question
16. Mach true statement about ecthyma:
Answer
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a. Infection caused by Candida
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b. Staphylococcal infection
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c. Mixed streptococcal and staphylococcal infection
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d. Symptom of deep fungal infection
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e. Symptom of early syphilis
Question 17
Question
17. 45 year-old male patient is manifesting homogenous erythematous patch on the chest that spreads peripherally from the centrally located small papule. There is a tendency to central clearing, the diameter of the whole lesion is 6 centimeters. According to the patient the lesion appeared around 4 weeks ago. There is no infiltration, no fever, no other complains. The patient does not recognize any causing factors, he works as a forester. Mark the most probable diagnosis:
Question 18
Question
18. The following are side effects of acitretin:
Question 19
Question
19. Intraepidermal blisters are the histological features of:
Answer
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a. acanthosis
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b. epidermotropism
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c. lichenification
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d. acantholysis
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e. hyperkeratosis
Question 20
Question
20. VDRL (-), FTA-ABS (+), TPHA (-): one can diagnose:
Question 21
Question
21. During the treatment of acne with isotretinoin in 20-year old female patients:
Answer
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a. photoprotection is strongly recommended
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b. tetracycline should be added to improve the efficiency of treatment
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c. contraception should be used for the entire treatment period and 2 weeks thereafter, blood levels of aminotransferases should be checked
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d. blood morphology has to be checked regularly
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e. contraception should be used for the entire treatment period and 2 months thereafter, blood levels of triglyceride and cholesterol should be checked
Question 22
Question
22. Which of the following pigmented skin lesions is the most suspicious of being a melanoma:
Answer
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a. Mole with uniform pigmentation
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b. Elevated mole
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c. Mole with diameter = 8 mm
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d. Mole with irregular border
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e. Growing mole
Question 23
Question
23. In which case it is obligatory to order body CT scans and check the lymph-nodes
Question 24
Question
24. Anticentromere antibodies (ACA) occur in patients with:
Question 25
Question
25. A 44 year old patient with by blisters on the skin and mucous membranes. The blisters rupture easily, leaving open sores. Microbiological tests revealed that there are no pathogenic bacterias on both affected and healthy skin. Blood tests revealed antibodies known as desmogleins. Which diagnosis is the most probable:
Answer
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a. MCTD
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b. Urticaria
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c. Pemphigus vulgaris
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d. Zoster
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e. SLE
Question 26
Question
26. Dyskeratosis it is:
Answer
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a. feature of psoriasis
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b. feature of lichen planus
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c. Balloon degeneration of keratinocytes
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d. keratinization of single cell within living layers of epidermis
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e. otherwise the Koebner symptom
Question 27
Question
27. Which sentence is true:
Answer
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a. Majority of skin lymphomas are B-cell lymphomas
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b. Majority of skin lymphomas are T-cell lymphomas
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c. Skin t-cell lymphomas affects young individuals mainly
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d. Mycosis fungoides is always treated with chemotherapy
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e. Lentigo-malignant melanoma is one of the most aggressive types of melanoma
Question 28
Question
28. Which of the following human leukocyte antigens is most often associated with type I psoriasis:
Answer
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a. HLA-Cw2
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b. HLA-B13
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c. HLA-B27
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d. HLA-B57
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e. HLA-Cw6
Question 29
Question
29. Main criterias of systemic lupus erythematosus do not include:
Question 30
Question
30. Match false statement describing antinuclear antibodies (ANA):
Answer
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a. They can be induced by some drugs
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b. They can be transmitted through placenta
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c. Their occurrence can be affected by other diseases like infections
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d. They are detected by indirect immunofluorescence
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e. Occur in all patients with discoid lupus erythematosus
Question 31
Question
31. Match true correlation(s) between connective tissue diseases and types of antinuclear antibodies:
Answer
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a. dermatomiositis - Mi-2 antibodies / SCLE - La (SS-B) antibodies
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b. systemic lupus erythematosus - anticentromere antibodies
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c. Pemphigus- MI2 antibodie, Pemphigoid- desmoglein antibodies
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d. Sclerodermia- ds DNA antibodies, ssDNA antibodies
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e. systemic scleroderma - Ro (SS-A) antibodies
Question 32
Question
32. A 77 year old male patient with nodular tumor with pearly border, dilated blood vessels and a central ulceration, present on the scalp for 9 months. The most probable diagnosis:
Question 33
Question
33. Which of the following are malignant disorders suspected to be metastatic disease:
Answer
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a. Cutaneous horn and Duhring disease
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b. Melanoma Clark V and patch phase of mycosis fungoides
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c. Basal cell cancer and infiltrative phase of mycosis fungoides
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d. Tumoral phase of mycosis fungoides and melanoma Clark IV
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e. Sezary syndrome and Stevens-Johnson syndrome
Question 34
Question
35. IgA antibodies against tissue transglutaminase are the hallmark of:
Question 35
Question
36. Sezary syndrome:
Answer
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a. Requires chemotherapy
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b. Is characterized by presence of ssDNA antibodies in the blood
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c. Is the B-cell lymphoma
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d. Can be treated by PUVA-therapy
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e. Can be diagnosed when erythrodermia and enlargement of lymph-nodes are found
Question 36
Question
37. Mark the target antigen(s) for autoimmunological reactions in pemphigus vulgaris:
Answer
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a. Desmoglein 3
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b. Desmoglein 1
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c. Collagen XVII
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d. Laminin 6
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e. Desmoglein 1 and 3
Question 37
Question
38. Erythrasma is a/an:
Answer
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a. erythematic lesions in body folds caused by Corynebacterium minutissimum
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b. skin changes due to seborrheic dermatitis
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c. skin lesions in the first stage of boreliosis
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d. skin lesions of the trunk caused by Malassezia
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e. infection of the scalp caused by Malassezia
Question 38
Question
39. Immunological disorders, diabetes mellitus, pregnancy, chronic steroid and antibiotic therapy, wearing dentures are main the risk factors of:
Answer
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a. Oral candidiasis
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b. Pemphigus vulgaris
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c. Cranial herpes zoster
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d. Leukoplakia
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e. Mucosal lichen planus
Question 39
Question
40. Mark the most common trigger in pediatric acute urticaria:
Question 40
Question
41. The 58-year old female patient manifests the erythematous skin lesion on left leg, which has a sharply demarcated raised edge. It appears as a red, swollen, warm, hardened and painful. There is a high fever, symptoms and lesion on the leg appeared a week ago. One can diagnose:
Answer
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a. Lyme boreliosis
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b. Lichen planus
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c. Mycosis fungoides
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d. Erysipelas
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e. Psoriasis
Question 41
Question
42. What is the “window period”. Choose the correct answer:
Answer
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a. Unprotected sex with a person during the window period is 100% safe
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b. During this period the infected patient always has positive HIV antibodies
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c. Period between HIV infection and the beginning of antibody production
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d. May last up to 2 years
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e. Period between HIV infection and the beginning of AIDS symptoms
Question 42
Question
43. Urticaria with a sudden onset and symptoms lasting less than 6 weeks is a definition:
Question 43
Question
44. Seronegative period in primary syphilis lasts from 3 weeks till:
Answer
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6 weeks
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7 weeks
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8 weeks
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9 weeks
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5 weeks
Question 44
Question
45. The primary lesion in psoriasis is a:
Answer
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a. Pustula
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b. Macula
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c. Papule
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d. Patch
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e. Scale
Question 45
Question
46. Nontreponemal serological tests are:
Answer
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a. VDRL, TPHA, FTA
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b. FTA-ABS, TPHA, RPR
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c. USR, VDRL, RPR
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d. VDRL, FTA, USR
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e. USR, TPHA, VDRL
Question 46
Question
47. What is not the risk factor for melanoma:
Answer
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a. Sunburns
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b. Large numbers of benign moles
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c. Atypical mole
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d. Skin type V according to Fitzpatrick
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e. Skin type I according to Fitzpatrick
Question 47
Question
48. Macerated, inflammatory lesions with satellite papules localized under the breast in obese women are probably the symptoms of:
Question 48
Question
49. A 6-year old male patient diagnosed with atopic dermatitis manifests additional skin lesions - erosions covered by golden - yellow crusts located on all the face area. One might diagnose:
Question 49
Question
50. Which mole should immediately be surgically removed:
Answer
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a. Diameter greater than 6 mm, uniform pigmentation and borders, elevated surface
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b. Localized on the acral parts of the body
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c. mole with hairs , elevated surface
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d. Diameter smaller than 6 mm, regular border
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e. Diameter greater than 6 mm, changing colour, asymetric shape
Question 50
Question
51. A 40-year-old male presents to clinic with a rash on the scalp, extensor elbows, knees and umbilicus. You note sharply demarcated erythematous plaques with silvery scale in those locations; there is no central clearing, no itching. The soles of the feet are normal. What is the most likely diagnosis?
Question 51
Question
52. Mark the laboratory findings not characteristic for SLE :
Answer
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a. High levels of dsDNA antibodies
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b. Acantholysis
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c. Positive photo-tests (indicating increased photosensitivity)
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d. Pancytopeny (decreased levels of RBC, WBC, Platelets)
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e. Proteinuria >0.5 g daily
Question 52
Question
53. Which of the following is not an IgE mediated allergic reaction:
Answer
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a. Atopic dermatitis
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b. Rhinitis
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c. Systemic anaphylaxis
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d. Acute urticaria
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e. Contact dermatitis
Question 53
Question
54. Choose the example of zoophilic infection:
Question 54
Question
55. Mark true sentence:
Answer
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a. Urticaria is an example of type IV of immunological reaction
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b. In majority of cases with atopic dermatitis IgE levels are normal
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c. Nickel sulfate is a rare cause of contact dermatitis
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d. Contact dermatitis is an example of type IV of immunological reaction
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e. Antihistaminic drugs are used in each case of contact dermatitis
Question 55
Question
56. Which sentence is true:
Answer
-
a. squamous-cell cancer is characterized by pearly border and teleangiectasia on the surface
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b. leucoplakia can be easily removed during examination
-
c. squamous cell cancer usually affects lower lip
-
d. Basal-cell cancer affects usually middle-age individuals
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e. the risk for squamous cell cancer is 90% when actinic keratosis is found
Question 56
Question
57. Which sentence is true:
Answer
-
A. Majority of skin lymphomas are B-cell lymphomas
-
B. Mycosis fungoides is always treated with chemotherapy
-
C. Majority of skin lymphomas are T-cell lymphomas
-
D. Skin t-cell lymphomas affects young individuals mainly
-
E. Mycosis fungoides is always treated with anti-fungal
Question 57
Question
58. A 77-year old male patient manifests disease as general erythroderma, lymphadenopathy, hepatomegaly, intense itching. The symptoms are present for few months. According to the patient's history disease he has been affected with contact dermatitis for many years. You can diagnose the most probable skin disorder:
Question 58
Question
59. Which of the following melanoma types is the most frequent:
Answer
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a. Nodular
-
b. Mucosal
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c. Superficial-spreading
-
d. Amelanocytic
-
e. Acral
Question 59
Question
60. The first line of treatment of erysipelas is/are:
Answer
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a. Crystalline penicillin
-
b. Erythromycin
-
c. Crystalline penicillin + clindamycin
-
d. Ceftriaxone + clindamycin
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e. Hydrocortisone
Question 60
Question
There was a question like - if the mother has anti La SS-b antibodies what is it likely for her infant to have?