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Gen Vet Med Midterm 2

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Gen Vet Med Quiz on Gen Vet Med Midterm 2, created by karahm on 30/01/2014.
karahm
Quiz by karahm, updated more than 1 year ago
karahm
Created by karahm over 11 years ago
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Question 1

Question
Which of the following is NOT a major mast cell mediator?
Answer
  • Heparin
  • Arachadonic acid
  • Platelet activating factor
  • Neutrophilic chemotactic factor
  • Lymphocytic chemotactic factor
  • Serine proteases

Question 2

Question
Which of the following are effects of histamine? Check all that apply.
Answer
  • Stimulates nitric oxide production (potent vasodilator)
  • Enhances leukocyte chemotaxis
  • Produces arachadonic acid metabolites
  • Stimulates smooth muscle contraction (bronchi, small intestines, pulmonary vasoconstriction)
  • Causes decreased vascular permeability

Question 3

Question
Leukotrienes are metabolites of arachadonic acid that are potent bronchoconstrictors.
Answer
  • True
  • False

Question 4

Question
Which of the following pairings is INCORRECT?
Answer
  • Serine proteases- destroy nearby cells and activate complement
  • Kinins- stimulate pain receptors
  • Cytokines- regulate storage and release of vasoactive mediators
  • Heparin- acts as anticoagulant

Question 5

Question
Generally, the onset of anaphylaxis is not related to severity of signs.
Answer
  • True
  • False

Question 6

Question
Localized anaphylaxis has evidence of generalized mediator release restricted to cutaneous findings alone. Which of the following is NOT one of these findings?
Answer
  • Erythema
  • Pruritis
  • Urticaria
  • Angioedema
  • These are all appropriate cutaneous findings, Karah. Get it together!

Question 7

Question
Which of the following are true regarding epinephrine for systemic anaphylaxis? Check all that apply.
Answer
  • Blocks effects of mediators
  • Reduces further mast cell degranulation
  • Increases cardiac output
  • Promotes bronhoconstriction
  • Peripheral vasodilation
  • IV dose of 1 mg/ml concentration is 0.05-0.1 ml/10 lbs

Question 8

Question
When treating anaphylaxis with crystalloid IV fluids it is important that systolic blood pressure is maintained at >80 mmHg.
Answer
  • True
  • False

Question 9

Question
Which of the following is the anti-inflammatory dose of dexamethasone SP for treatment of anaphylaxis?
Answer
  • 0.1-0.2 mg/kg IV
  • 0.5-1 mg/kg IV
  • 0.1-0.2 mg/kg IM
  • 0.5-1 mg/kg IM

Question 10

Question
The IM dose of diphenhydramine for systemic anaphylaxis is 1-2 mg/kg.
Answer
  • True
  • False

Question 11

Question
What drug can we use to manage persistent bradycardia with systemic anaphylaxis?
Answer
  • Atropine, 0.02-0.04 mg/kg IV, IM
  • Atropine, 0.2-0.4 mg/kg IV, IM
  • Dobutamine, 5-10 mcg/kg/min IV (constant rate infusion)
  • Dobutamine, 0.5-1 mcg/kg/min IV (constant rate infusion)

Question 12

Question
Aminophylline/theophyylline is a bronchodilator given IM or IV (slowly) at 4-8 mg/kg.
Answer
  • True
  • False

Question 13

Question
What is the dose for oral diphenhydramine for treatment of localized anaphylaxis?
Answer
  • 1 mg/lb q 8 hrs until all signs are clear
  • 1 mg/kg q 8 hrs until all signs are clear
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