Question 1
Question
The main enzymes targets for regulation in the krebs cycle are:
Answer
-
citrate synthase and fumarase
-
Aconitase, succinate dehydrogenase and fumarase
-
citrate synthase, isocitrate dehydrogenase and alpha ketoglutarate dehydrogenase
-
isocitrate dehydrogenase and alpha ketoglutarate dehydrogenase
Question 2
Question
Sodium fluoroacetate is...
Answer
-
part of the krebs cycle
-
an enzyme in the krebs cycle
-
A poison which disrupts the krebs cycle
-
Naturally in the body and is an activator of the krebs cycle
Question 3
Question
Beriberi is a vitamin C deficiency characterised by neurological and cardiac symptoms
Question 4
Question
Leigh's syndrome is a fatal neurodegenerative disorder caused by inherited faults in oxidative phosporylation. The pathology of the disease is bilateral lesions. Where are these found?
Answer
-
thalamus, Basal ganglia and brain stem and spinal cord
-
thalamous, Basal ganglia and brain stem
-
brain stem, basal ganglia and spinal cord
-
spinal cord and brain stem
Question 5
Question
Electrons used in oxidative phosphorylation come from...?
Question 6
Question
Complex two pumps out 2 hydrogen ions for every 2 electrons
Question 7
Question
The krebs cycle can be regulated by hormones
Question 8
Question
What is Beriberi?
Answer
-
A vitamin C deficiency- characterised by neurological and cardiac symptoms
-
A vitamin b1 deficiency- characterised by neurological and cardiac symptoms
-
A vitamin b1 deficiency- characterised by muscle wasting
-
A vitamin C deficiency- characterised by muscle wasting
Question 9
Question
The main target for regulation in the krebs cycle is on the reactions that are reversible
Question 10
Question
The PDH is inactive when bound to phosphate
Question 11
Question
The PDH is required in the krebs cycle for the following reaction to take place; oxaloacetate+ acetyl CoA ---> citrate
Question 12
Question
Which of the following are the steps which are regulated in glycolysis?
Answer
-
glucose to glucose-6-phosphate
-
glucose-6-phosphate to fructose-6-phosphate
-
fructose-6-phosphate to fructose-1,6-bisphosphate
-
3-phosphoglycerate to 2-phosphoglycerate
-
phosphoenolpyruvate to pyruvate
Question 13
Question
Arsenate will substitute for phosphate in 3- phosphoglycerate
Question 14
Question
Arsenate is a bad because it makes the net ATP production from the krebs cycle be 0
Question 15
Question
The net ATP production of glycolysis is 2