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Created by Amaal Salhieh
over 9 years ago
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| Question | Answer |
| List bacteriostatic Abx | My brain went static during the CC TEST Chloramphenicol Clindamycin Tetracyclines Erythromycin Sulfonamides Trimethoprim Clindamycin tried meth (TRIMETHoprim), and rode her tetracycline into the -static pool, while she a-wrist-throwed (erythro) sulfur and chloramphenicol into the pool |
| List bactericidal Abx | Rif and Quin, amino killers (-cidal), drove the Van bc it was Beta than the Metro Rifampin Quinolones Aminoglycosides Vancomycin Beta-lactams Metronidazole |
| Endotoxins | Released by gram negative bac. Assist disease process |
| Name 3 bac. that don't fully form a cell wall | Chlamydia Rickettsia Mycoplasma |
| SCV | Slow-growing subpopulation of bacteria with distinctive traits Atypical colony morphology & unusual biochem characteristics Propensity to invade and persist within host cells w/o stimulating significant host responses or inducing cell lysis Causes persisting or recurrent infections on emergence from protective environment |
| What contains sterol? | Fungii (& mycoplasma) |
| Inhibition of transpeptidation | Beta-lactams bind to PBP |
| Inhibition of peptidoglycan precursor synthesis | I VOTD for my pep dog (pet dog) Vancomycin Oritavancin Televancin Dalbavancin |
| 30s | Our TA is in her 30s Tetracyclines Aminoglycosides |
| Aminoglycosides | 30s --> misread mRNA My amino misread my RNA(me) (My amigo misread my name) |
| Tetracycline | 30s --> blocks attachment to tRNA Tetracycline, T-RNA (T & T) While I was riding my tetracycline, the blocked the street tRNA |
| Chloramphenicol | 50s-->inhibits peptidyl transferase The chloramphenicol (chlorine) in the pool inhibits the transfer of pepTIDEs |
| 50s | Chloramphenicol Macrolides Clindamycin Pristinamycins (Also, Quinipristin according to Abx I) Clinda through the Quin of ACEs (macrolides) into the pristin, chlorinated pool at the 50 end Macrolides - ACE (arithro, clarithro, erythro) |
| 50s-->block elongation | Macrolides Clindamycin Pristinamycins The Macro PC was blocked for a(n) eLONGation time |
| fMET-tRNA | Linezolid, Tedizolid I met Ted in Line |
| Inhibition of nucleic acid synthesis | SMRT Q Sulfonamides Metronidazole Rifampin TMP-SMX Quinolones It's SMRT to inhibit nuQleic acids |
| Concentration-Dependent Killing | Rate and extent of killing increases as the peak [drug] increases |
| Time-Dependent Killing | Bactericidal as long as [plasma] > MBC [Drug] should be maintained above MIC for entire time interval between repetitive doses |
| Increases bleeding w/ warfarin | QSMM Quin Sulfa has Macro bleeding when she takes the Metro Quinolones Sulfa Macrolides Metronidazole |
| Decreases bleeding w/ warfarin) | Some penicillin and Rifampin Sticking a Rif (rough) Pencillin in a vessel will surely cause a clot |
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