5357385
Description
Flashcards by Amaal Salhieh, updated more than 1 year ago
|
Created by Amaal Salhieh
over 9 years ago
|
|
| Question | Answer |
| Neutropenic patients are susceptible to.. (general) | pyogenic, extracellular bacteria some opportunistic fungi |
| Define ANC | <500/mm3 |
| Neutropenic fever symptoms | Fever and low ANC |
| Neutropenic fever Treatment | Broad-spectrum penicillin Piperacillin-tazobactam (most commonly used), Cefepime, Ceftaz, maybe a carbapenem Add MRSA coverage if concern |
| Impaired CMI types of infections | Intracellular - ~Listeria, Legionella, some mycobacteria (M. tuberculosis, M. leprae) Viruses ~Herpes ~Certain resp. viruses (RSV. parainflu) Fungi like endemic mycoses (histo, cocci, blasto) parasites like toxoplasma gondii Extracellular ~Aspergillus, Candida |
| Impaired Humoral Immunity types of infections (general) | Encapsulated bacteria S. pneumoniae, H. influenzae |
| Asplenia have high risk to... (infections) | S. pneumoniae H. influenzae Neisseria meningitidis |
| Early onset GBS | meningitis pneumonia bacteremia |
| Late onset GBS | meningitis and bacteremia |
| GBS Treatment | Usually susceptible to penicillin |
| GBS Prophylaxis (no allergy) | Penicillin G |
| GBS Penicillin-allergic (rash) | Cefazolin Such a spaz for getting the rash |
| GBS penicillin allergic (anaphylaxis) | Clindamycin When it's serious, you call Linda for help |
| Where does GBS colonize? | Lower GI & GU tracts 10-30% of pregnant women vaginas |
| How do you perform a CAMP test? | Streak S. aureus down the center. Streak GBS perpendicular to it. W/ GBS, you would see enhanced hemolysis (CAMP test-positive) |
| Microbio of Listeria | Gram positive, short, regular bacillus Motile at 25, less at 37 Facultative intracellular |
| Listeria Pathogenesis | Listeriolysin O Goes from one cell to the next by coordinating actin assembly to push bacteria to cell membrane |
| Granulomatosis infantiseptica | Found with early onset Listeria Disseminated granulomas & abscesses with high mortality |
| Listeria Symptoms in Pregnant Women | Fevers, chills, nonspecific symptoms |
| Neonates Late Onset of Listeria | meningitis with sepsis |
| Listeria Treatment | Ampicillin or Penicillin G TMP-SMX If meningitis, need ampicillin and either TMP-SMX or gentamicin bc ampicillin is low in CSF |
Want to create your own Flashcards for free with GoConqr? Learn more.